Purely cutaneous Langerhans cell histiocytosis presenting as an ulcer on the chin in an elderly man successfully treated with thalidomide

• Main Authors: Radhakrishnan Subramaniyan, Rajagopal Ramachandran, Gnanasekaran Rajangam, Navya Donaparthi
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2015-01-01
• Series: Indian Dermatology Online Journal
• Subjects: Cutaneous; elderly; Langerhans cell histiocytosis; perioral lesion; thalidomide
• Online Access: http://www.idoj.in/article.asp?issn=2229-5178;year=2015;volume=6;issue=6;spage=407;epage=409;aulast=Subramaniyan

Langerhans cell histiocytosis (LCH) is a rare, clonal proliferative disorder of Langerhans' cells of unknown etiology. Although the clinical presentation and therapeutic approach to the disease in children have been well established; limited data is available about the disease in adults. Purely cutaneous involvement of LCH in a man older than 70 years has rarely been described. Herein we report the case of a 71-year-old man with cutaneous LCH confined to the perioral region, scalp, and flexures successfully treated with thalidomide.