Assessment of 5-lipoxygenase involvement in human monocyte-mediated LDL oxidation.
Lipoxygenase (LO) activity has been implicated in the process by which activated human monocytes oxidize normal human low density lipoprotein (LDL) and render it toxic to target cells. Here we examined the role of 5-LO in activated monocyte-mediated LDL modification. Five putative inhibitors of 5-LO...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1993-01-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520413203 |