Concurrent EPA and DHA Supplementation Impairs Brown Adipogenesis of C2C12 Cells

Concurrent EPA and DHA Supplementation Impairs Brown Adipogenesis of C2C12 Cells

Maternal dietary supplementation of n−3 polyunsaturated fatty acids (n−3 PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), is considered to play positive roles in fetal neuro system development. However, maternal n−3 PUFAs may induce molecular reprogramming of uncommitte...

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Bibliographic Details
Main Authors: Saeed Ghnaimawi, Jamie Baum, Rohana Liyanage, Yan Huang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Genetics
Subjects:
n-3 PUFAs
C2C12 cells
brown adipogenesis
metabolism
mitochondrial function
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2020.00531/full

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