The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma

The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma

Abstract Background This study aimed to confirm that blocking RasGRP4 can effectively slow down the growth of DLBCL both in vitro and in vivo and ascertain the role of RasGRP4 in the prognosis of DLBCL clinically. Methods RasGRP4 expression levels were examined in benign tissues and lymphomas. In or...

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Bibliographic Details
Main Authors: Lin Zhu, Chunyan Xia, Lin Wu, Yuxuan Zhang, Junling Liu, Yinan Chen, Jing Liu, Yongxin Xiao, Kai Nie, Liyu Huang, Ning Qu, Hong Yu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Cell Communication and Signaling
Subjects:
RasGRP4
DLBCL
MAPK
Proliferation
Prognosis
Online Access:http://link.springer.com/article/10.1186/s12964-019-0415-6

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