Ultra-early amplitude decrement after repetitive nerve stimulation supports early neuromuscular junction injury in amyotrophic lateral sclerosis: a prospective cross-sectional study

Ultra-early amplitude decrement after repetitive nerve stimulation supports early neuromuscular junction injury in amyotrophic lateral sclerosis: a prospective cross-sectional study

The dying-back hypothesis holds that the damage to neuromuscular junctions and distal axons in amyotrophic lateral sclerosis occurs at the earliest stage of the disease. Previous basic studies have confirmed early damage to neuromuscular junctions, but it is difficult to obtain such evidence directl...

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Bibliographic Details
Main Authors: Jing-Yue Ma, Xiang-Yi Liu, Shuo Zhang, Dong-Sheng Fan
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2022-01-01
Series:Neural Regeneration Research
Subjects:
amplitude decremental response; amyotrophic lateral sclerosis; dying-back hypothesis; motor neuron disease; nerve electrophysiology; physiopathology; prognosis; repetitive nerve stimulation
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=3;spage=655;epage=660;aulast=Ma

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2022;volume=17;issue=3;spage=655;epage=660;aulast=Ma

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