Intracerebroventricularly-administered 1-methyl-4-phenylpyridinium ion and brain-derived neurotrophic factor affect catecholaminergic nerve terminals and neurogenesis in the hippocampus, striatum and substantia nigra

Intracerebroventricularly-administered 1-methyl-4-phenylpyridinium ion and brain-derived neurotrophic factor affect catecholaminergic nerve terminals and neurogenesis in the hippocampus, striatum and substantia nigra

Parkinson's disease is a progressive neurological disease characterized by the degeneration of dopaminergic neurons in the substantia nigra. A highly similar pattern of neurodegeneration can be induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) or 1-methyl-4-phenylpyridinium ion (MP...

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Bibliographic Details
Main Authors: Jun-Fang Chen, Man Wang, Ying-Han Zhuang, Thomas Behnisch
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2018-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; Parkinson′s disease; MPTP; brain-derived neurotrophic factor; intracerebroventricular infusion; dopaminergic fibers; norepinephrine; tyrosine hydroxylase; hippocampus; substantia nigra; striatum; neurogenesis; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2018;volume=13;issue=4;spage=717;epage=726;aulast=Chen

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