WNT10A plays an oncogenic role in renal cell carcinoma by activating WNT/β-catenin pathway.

Renal cell carcinoma (RCC) is a malignancy with poor prognosis. WNT/β-catenin signaling dysregulation, especially β-catenin overactivation and WNT antagonist silencing, is associated with RCC carcinogenesis and progression. However, the role of WNT ligands in RCC has not yet been determined. We scre...

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Bibliographic Details
Main Authors: Ren-Jun Hsu, Jar-Yi Ho, Tai-Lung Cha, Dah-Shyong Yu, Chieh-Lin Wu, Wei-Ping Huang, Pauling Chu, Ying-Hsin Chen, Jiann-Torng Chen, Cheng-Ping Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3477117?pdf=render

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