(p)ppGpp: Magic Modulators of Bacterial Physiology and Metabolism

(p)ppGpp: Magic Modulators of Bacterial Physiology and Metabolism

When bacteria experience growth-limiting environmental conditions, the synthesis of the hyperphosphorylated guanosine derivatives (p)ppGpp is induced by enzymes of the RelA/SpoT homology (RSH)-type protein family. High levels of (p)ppGpp induce a process called “stringent response”, a major cellular...

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Bibliographic Details
Main Authors: Wieland Steinchen, Victor Zegarra, Gert Bange
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-09-01
Series:Frontiers in Microbiology
Subjects:
stringent response
(p)ppGpp
alarmones
metabolism
physiology
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.02072/full

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