Whole Genome Sequencing of Giant Schnauzer Dogs with Progressive Retinal Atrophy Establishes <i>NECAP1</i> as a Novel Candidate Gene for Retinal Degeneration

Whole Genome Sequencing of Giant Schnauzer Dogs with Progressive Retinal Atrophy Establishes <i>NECAP1</i> as a Novel Candidate Gene for Retinal Degeneration

Canine progressive retinal atrophies (PRA) are genetically heterogeneous diseases characterized by retinal degeneration and subsequent blindness. PRAs are untreatable and affect multiple dog breeds, significantly impacting welfare. Three out of seven Giant Schnauzer (GS) littermates presented with P...

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Bibliographic Details
Main Authors: Rebekkah J. Hitti, James A. C. Oliver, Ellen C. Schofield, Anina Bauer, Maria Kaukonen, Oliver P. Forman, Tosso Leeb, Hannes Lohi, Louise M. Burmeister, David Sargan, Cathryn S. Mellersh
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Genes
Subjects:
canine
dog
progressive retinal atrophy
PRA
retinal degeneration
Online Access:https://www.mdpi.com/2073-4425/10/5/385

Internet

https://www.mdpi.com/2073-4425/10/5/385

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