CCL2 upregulation triggers hypoxic preconditioning-induced protection from stroke

<p>Abstract</p> <p>Background</p> <p>A brief exposure to systemic hypoxia (i.e., hypoxic preconditioning; HPC) prior to transient middle cerebral artery occlusion (tMCAo) reduces infarct volume, blood-brain barrier disruption, and leukocyte migration. CCL2 (MCP-1), typi...

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Bibliographic Details
Main Authors: Stowe Ann M, Wacker Bradley K, Cravens Petra D, Perfater Jennifer L, Li Min K, Hu Ruilong, Freie Angela B, Stüve Olaf, Gidday Jeffrey M
Format: Article
Language:English
Published: BMC 2012-02-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/9/1/33