A review of the use of Streptozotocin (STZ) in the induction of diabetes in rats and subsequent ocular tissue changes

Streptozotocin is widely used in medical research for treating certain cancers of the Islets of Langerhans and to produce an animal model for type 1 diabetes. A study has revealed that when compared to the control group of rats, those injected with STZ exhibited reduced plasma insulin and elevated b...

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Bibliographic Details
Main Author: H. L. Sithole
Format: Article
Language:English
Published: AOSIS 2009-12-01
Series:African Vision and Eye Health
Subjects:
Online Access:https://avehjournal.org/index.php/aveh/article/view/156