Resveratrol Enhances Neurite Outgrowth and Synaptogenesis Via Sonic Hedgehog Signaling Following Oxygen-Glucose Deprivation/Reoxygenation Injury

Resveratrol Enhances Neurite Outgrowth and Synaptogenesis Via Sonic Hedgehog Signaling Following Oxygen-Glucose Deprivation/Reoxygenation Injury

Background/Aims: Neurite outgrowth and synaptogenesis are critical steps for functional recovery after stroke. Resveratrol promotes neurite outgrowth and synaptogenesis, but the underlying mechanism is not well understood, although the Sonic hedgehog (Shh) signaling pathway may be involved. Given th...

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Bibliographic Details
Main Authors: Fanren Tang, Shuang Guo, Hongyan Liao, Pingping Yu, Li Wang, Xiaosong Song, Jixiang Chen, Qin Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Resveratrol
Neuron
Sonic hedgehog signaling
Neurite outgrowth
Synaptogenesis
Cyclopamine
Purmophamine
Sirtinol
Sirt1
Online Access:https://www.karger.com/Article/FullText/481611

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