Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death

Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death

Most chemotherapeutic agents, including gemcitabine, do not elicit immunogenic cell death, a phenomenon associated with the release of damage-associated molecule patterns (DAMPs). Here, the authors show that gemcitabine-treated dying cancer cells express hallmark DAMPs but their immunogenic properti...

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Bibliographic Details
Main Authors: K. Hayashi, F. Nikolos, Y. C. Lee, A. Jain, E. Tsouko, H. Gao, A. Kasabyan, H. E. Leung, A. Osipov, S. Y. Jung, A. V. Kurtova, K. S. Chan
Format: Article
Language:English
Published: Nature Publishing Group 2020-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19970-9

Internet

https://doi.org/10.1038/s41467-020-19970-9

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