Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death
Most chemotherapeutic agents, including gemcitabine, do not elicit immunogenic cell death, a phenomenon associated with the release of damage-associated molecule patterns (DAMPs). Here, the authors show that gemcitabine-treated dying cancer cells express hallmark DAMPs but their immunogenic properti...
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Bibliographic Details
Main Authors: |
K. Hayashi,
F. Nikolos,
Y. C. Lee,
A. Jain,
E. Tsouko,
H. Gao,
A. Kasabyan,
H. E. Leung,
A. Osipov,
S. Y. Jung,
A. V. Kurtova,
K. S. Chan |
Format: | Article
|
Language: | English |
Published: |
Nature Publishing Group
2020-12-01
|
Series: | Nature Communications
|
Online Access: | https://doi.org/10.1038/s41467-020-19970-9
|