Dysregulation of Leukocyte Trafficking in Type 2 Diabetes: Mechanisms and Potential Therapeutic Avenues

Dysregulation of Leukocyte Trafficking in Type 2 Diabetes: Mechanisms and Potential Therapeutic Avenues

Type 2 Diabetes Mellitus (T2DM) is a chronic inflammatory disorder that is characterized by chronic hyperglycemia and impaired insulin signaling which in addition to be caused by common metabolic dysregulations, have also been associated to changes in various immune cell number, function and activat...

Full description

Bibliographic Details
Main Authors:	Laleh Pezhman, Abd Tahrani, Myriam Chimen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Series:	Frontiers in Cell and Developmental Biology
Subjects:	therapies inflammation type 2 diabetes obesity trafficking leukocyte
Online Access:	https://www.frontiersin.org/articles/10.3389/fcell.2021.624184/full

Similar Items

Changes in Circadian Rhythms Dysregulate Inflammation in Ageing: Focus on Leukocyte Trafficking
by: Poppy Nathan, et al.
Published: (2021-05-01)

Interactions between CD44 and hyaluronan in leukocyte trafficking
by: Braedon eMcDonald, et al.
Published: (2015-02-01)

Visualising leukocyte trafficking in the living brain with 2-photon intravital microscopy
by: Saparna ePai, et al.
Published: (2013-01-01)

The association between overweight/obesity and double diabetes in adults with type 1 diabetes; a cross-sectional study
by: Nathan WP Cantley, et al.
Published: (2021-09-01)

Sodium-glucose co-transporter-2 inhibitors in patients with type 2 diabetes mellitus without established cardiovascular disease: Do they have a role in primary prevention?
by: Shailaja Kale, et al.
Published: (2021-06-01)

Beta2-Integrins and Interacting Proteins in Leukocyte Trafficking, Immune Suppression, and Immunodeficiency Disease
by: Susanna C. Fagerholm, et al.
Published: (2019-02-01)

Vascular Endothelial Galectins in Leukocyte Trafficking
by: Abbey Lightfoot, et al.
Published: (2021-06-01)

Leukocyte Trafficking and Regulation of Murine Hematopoietic Stem Cells and Their Niches
by: Daniel Lucas, et al.
Published: (2019-03-01)

The Role of Leukocytes in Diabetic Cardiomyopathy
by: Anamika Bajpai, et al.
Published: (2018-11-01)

Editorial: Leukocyte Trafficking in Homeostasis and Disease
by: Joaquin Teixidó, et al.
Published: (2019-11-01)

Imaging of leukocyte trafficking in Alzheimer’s disease
by: Gabriela eConstantin, et al.
Published: (2016-02-01)

Leukocytes Breach Endothelial Barriers by Insertion of Nuclear Lobes and Disassembly of Endothelial Actin Filaments
by: Sagi Barzilai, et al.
Published: (2017-01-01)

The mitochondria-targeted antioxidant MitoQ modulates oxidative stress, inflammation and leukocyte-endothelium interactions in leukocytes isolated from type 2 diabetic patients
by: Irene Escribano-Lopez, et al.
Published: (2016-12-01)

Changes in Leukocyte Subpopulations with Decline in Glomerular Filtration Rate in Patients with Type 2 Diabetes
by: Manouchehr Nakhjavani, et al.
Published: (2015-10-01)

Microvascular complications in patients with type 2 diabetes : the impact of ethnicity, sleep and oxidative stress
by: Tahrani, Abd Al Magid
Published: (2013)

Prevalence of leukocytes in type 2 diabetic patients in Erbil City
by: Muhsin H Ubeid
Published: (2020-01-01)

Blood leukocyte composition and neutrophil to lymphocyte ratio in patients with newly diagnosed type 2 diabetes mellitus depending on the degree of overweight/obesity
by: O.V. Furmanova, et al.
Published: (2020-10-01)

Leukocyte Composition and Immunophenotype of the Blood Lymphocytes in Women with Type 2 Diabetes Mellitus and Obesity
by: Ya.A. Saienko, et al.
Published: (2016-08-01)

Leukocyte Trafficking in Homeostasis and Disease
Published: (2019)

Structure and Emerging Functions of LRCH Proteins in Leukocyte Biology
by: Thibaud Rivière, et al.
Published: (2020-09-01)

The SGLT2 Inhibitor Empagliflozin Ameliorates the Inflammatory Profile in Type 2 Diabetic Patients and Promotes an Antioxidant Response in Leukocytes
by: Francesca Iannantuoni, et al.
Published: (2019-11-01)

Triggering the Resolution of Immune Mediated Inflammatory Diseases: Can Targeting Leukocyte Migration Be the Answer?
by: Sophie J. Hopkin, et al.
Published: (2019-03-01)

Cardiac autonomic neuropathy in patients with diabetes mellitus: current perspectives
by: Fisher VL, et al.
Published: (2017-10-01)

Relation between leukocyte count, adiposity, and cardiorespiratory fitness in pubertal adolescents
by: Thiago Ricardo dos Santos Tenório, et al.

Editorial: Targeting Leukocyte Trafficking: Insights and Future Directions
by: Ronen Sumagin, et al.
Published: (2021-10-01)

Resolution of inflammation: leukocytes and molecular pathways as potential therapeutic targets
by: Janos G Filep
Published: (2013-08-01)

Peripheral Leukocytes and Intracerebral Hemorrhage
by: Adeoye, Opeolu, M.D.
Published: (2012)

The Yin and Yang of Tyrosine Kinase Inhibition During Experimental Polymicrobial Sepsis
by: Cassiano Felippe Gonçalves-de-Albuquerque, et al.
Published: (2018-04-01)

Human Leukocyte Antigens class II (HLA II) gene profile from an admixed population of patients with type 1 diabetes with severe diabetic retinopathy: a nested case-control study in Brazil
by: Deborah Conte Santos, et al.
Published: (2021-08-01)

Insights Into Leukocyte Trafficking in Inflammatory Arthritis – Imaging the Joint
by: Julia E. Manning, et al.
Published: (2021-03-01)

Structure and Immune Function of Afferent Lymphatics and Their Mechanistic Contribution to Dendritic Cell and T Cell Trafficking
by: Jorge Arasa, et al.
Published: (2021-05-01)

Reduced leukocyte telomere lengths and sirtuin 1 gene expression in long‐term survivors of type 1 diabetes: A Dialong substudy
by: Trine Baur Opstad, et al.
Published: (2021-07-01)

Role of Platelets in Leukocyte Recruitment and Resolution of Inflammation
by: Jan Rossaint, et al.
Published: (2018-11-01)

Downregulation of miR-31 in Diabetic Nephropathy and its Relationship with Inflammation
by: Susana Rovira-Llopis, et al.
Published: (2018-10-01)

Does bariatric surgery influence plasma levels of fetuin-A and leukocyte cell-derived chemotaxin-2 in patients with type 2 diabetes mellitus?
by: Hsien-Hao Huang, et al.
Published: (2018-06-01)

Juxtaposition of Coeliac Disease and Type 1 Diabetes; the Role of Shared Non-human Leukocyte Antigen Loci
by: Iraj Shahramian, et al.
Published: (2018-03-01)

Effect of Porphyromonas gingivalis infection on leukocyte count in rat model of diabetes mellitus
by: Safira Niza Ulfita, et al.
Published: (2018-12-01)

Alteration in blood leukocyte profile due to exercise and its implication
by: Ryoichi Nagatomi
Published: (2013-11-01)

Splenectomy is associated with altered leukocyte kinetics after severe trauma
by: Michel Paul Johan Teuben, et al.
Published: (2021-03-01)

News Coverage of Sex Trafficking in the US: The Portrayal of Sex Traffickers
by: Ta, Ngan
Published: (2014)