Phenotypic analysis of catastrophic childhood epilepsy genes
Griffin et al used CRISPR-Cas9 to generate 40 single-gene mutant zebrafish lines representing childhood epilepsies for which they evaluated larval phenotypes using electrophysiological, behavioral, neuro-anatomical, survival and pharmacological assays. Their study provides a useful resource for the...
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Bibliographic Details
| Main Authors: |
Aliesha Griffin,
Colleen Carpenter,
Jing Liu,
Rosalia Paterno,
Brian Grone,
Kyla Hamling,
Maia Moog,
Matthew T. Dinday,
Francisco Figueroa,
Mana Anvar,
Chinwendu Ononuju,
Tony Qu,
Scott C. Baraban |
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| Format: | Article
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| Language: | English |
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| Published: |
Nature Publishing Group
2021-06-01
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| Series: | Communications Biology
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| Online Access: | https://doi.org/10.1038/s42003-021-02221-y
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