Cytokines TNF-Alpha and IL-8 Gene Polymorphisms in Sickle Cell Anaemia Patients under Hydroxyurea Treatment

Introduction: Sickle Cell Anaemia (SCA) is an inherited disorder characterised by homozygosis for the mutation that causes Haemoglobin S (Hb S) production. SCA patients have increased serum levels of circulating Tumour Necrosis Factor Alpha (TNF-α) and Interleukin 8 (IL-8) during crisis events, occa...

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Bibliographic Details
Main Authors: Fathelrahman M Hassan, Faisal M Alzahrani
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-06-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11681/35740_CE(Ra1)_F(SS)_PF1(MJ_AP)_PN(AP).pdf