A novel diphtheria toxin‐based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma

A novel diphtheria toxin‐based bivalent human EGF fusion toxin for treatment of head and neck squamous cell carcinoma

Epidermal growth factor receptor (EGFR) is often overexpressed in head and neck squamous cell carcinoma (HNSCC) and represents a top candidate for targeted HNSCC therapy. However, the clinical effectiveness of current Food and Drug Administration (FDA)‐approved drugs targeting EGFR is moderate, and...

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Bibliographic Details
Main Authors: Zeng Qi, Yue Qiu, Zhaohui Wang, Huiping Zhang, Ling Lu, Yanqiu Liu, David Mathes, Elizabeth A. Pomfret, Dexiang Gao, Shi‐Long Lu, Zhirui Wang
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:Molecular Oncology
Subjects:
diphtheria toxin
EGF
EGFR
fusion toxin
head and neck cancer
HNSCC
Online Access:https://doi.org/10.1002/1878-0261.12919

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