The Dynamic Entropy of Tumor Immune Infiltrates: The Impact of Recirculation, Antigen-Specific Interactions, and Retention on T Cells in Tumors

The Dynamic Entropy of Tumor Immune Infiltrates: The Impact of Recirculation, Antigen-Specific Interactions, and Retention on T Cells in Tumors

Analysis of tumor infiltration using conventional methods reveals a snapshot view of lymphocyte interactions with the tumor environment. However, lymphocytes have the unique capacity for continued recirculation, exploring varied tissues for the presence of cognate antigens according to inflammatory...

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Bibliographic Details
Main Authors: Tiffany C. Blair, Alejandro F. Alice, Lauren Zebertavage, Marka R. Crittenden, Michael J. Gough
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
T cell
recirculation
tumor
clonality analysis
retention
recruitment
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.653625/full

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