Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient

SARS-CoV-2 emerged as a worldwide pandemic in late 2019 and initially was described as a primary respiratory illness. The clinical manifestations of COVID-19 are now known to encompass nearly all organ systems, including the central nervous system. We present a case of an allogeneic hematopoietic st...

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Main Authors: Fahmin Basher, Jose F Camargo, Meilin Diaz-Paez, Lazaros J Lekakis, Denise L Pereira
Format: Article
Language:English
Published: SAGE Publishing 2021-04-01
Series:Clinical Medicine Insights: Case Reports
Online Access:https://doi.org/10.1177/11795476211009811
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spelling doaj-bfb92433997c4ff59734f6bafc39d7442021-04-19T21:33:58ZengSAGE PublishingClinical Medicine Insights: Case Reports1179-54762021-04-011410.1177/11795476211009811Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant RecipientFahmin Basher0Jose F Camargo1Meilin Diaz-Paez2Lazaros J Lekakis3Denise L Pereira4Division of General Internal Medicine, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USADivision of Infectious Diseases, Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, USADivision of Transplantation and Cellular Therapy, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USADivision of Transplantation and Cellular Therapy, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USADivision of Transplantation and Cellular Therapy, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USASARS-CoV-2 emerged as a worldwide pandemic in late 2019 and initially was described as a primary respiratory illness. The clinical manifestations of COVID-19 are now known to encompass nearly all organ systems, including the central nervous system. We present a case of an allogeneic hematopoietic stem cell transplant recipient who recovered from documented SARS-CoV-2 infection and later presented with symptoms of meningitis. While cerebrospinal fluid analysis did not reveal any bacterial or viral etiologies, evidence of an inflammatory state, including ophthalmologic findings of episcleritis, indicate what is likely the first reported case of aseptic meningitis associated with SARS-CoV-2 infection after initial clinical recovery.https://doi.org/10.1177/11795476211009811
collection DOAJ
language English
format Article
sources DOAJ
author Fahmin Basher
Jose F Camargo
Meilin Diaz-Paez
Lazaros J Lekakis
Denise L Pereira
spellingShingle Fahmin Basher
Jose F Camargo
Meilin Diaz-Paez
Lazaros J Lekakis
Denise L Pereira
Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
Clinical Medicine Insights: Case Reports
author_facet Fahmin Basher
Jose F Camargo
Meilin Diaz-Paez
Lazaros J Lekakis
Denise L Pereira
author_sort Fahmin Basher
title Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
title_short Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
title_full Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
title_fullStr Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
title_full_unstemmed Aseptic Meningitis after Recovery from SARS-CoV-2 in an Allogeneic Stem Cell Transplant Recipient
title_sort aseptic meningitis after recovery from sars-cov-2 in an allogeneic stem cell transplant recipient
publisher SAGE Publishing
series Clinical Medicine Insights: Case Reports
issn 1179-5476
publishDate 2021-04-01
description SARS-CoV-2 emerged as a worldwide pandemic in late 2019 and initially was described as a primary respiratory illness. The clinical manifestations of COVID-19 are now known to encompass nearly all organ systems, including the central nervous system. We present a case of an allogeneic hematopoietic stem cell transplant recipient who recovered from documented SARS-CoV-2 infection and later presented with symptoms of meningitis. While cerebrospinal fluid analysis did not reveal any bacterial or viral etiologies, evidence of an inflammatory state, including ophthalmologic findings of episcleritis, indicate what is likely the first reported case of aseptic meningitis associated with SARS-CoV-2 infection after initial clinical recovery.
url https://doi.org/10.1177/11795476211009811
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