An optimised saliva collection method to produce high-yield, high-quality RNA for translational research.

An optimised saliva collection method to produce high-yield, high-quality RNA for translational research.

Saliva represents an ideal matrix for diagnostic biomarker development as it is readily available and requires no invasive collection procedures. However, salivary RNA is labile and rapidly degrades. Previous attempts to isolate RNA from saliva have yielded poor quality and low concentrations. Here...

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Bibliographic Details
Main Authors: Roisin Sullivan, Susan Heavey, David G Graham, Rachel Wellman, Saif Khan, Sri Thrumurthy, Benjamin S Simpson, Tina Baker, Sarah Jevons, Jose Ariza, Victor Eneh, Hayley Pye, Hayley Luxton, Rifat Hamoudi, Hayley Whitaker, Laurence B Lovat
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0229791

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https://doi.org/10.1371/journal.pone.0229791

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