Functional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline development.

CLK-2/TEL2 is essential for viability from yeasts to vertebrates, but its essential functions remain ill defined. CLK-2/TEL2 was initially implicated in telomere length regulation in budding yeast, but work in Caenorhabditis elegans has uncovered a function in DNA damage response signalling. Subsequ...

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Bibliographic Details
Main Authors: Sandra C Moser, Sophie von Elsner, Ingo Büssing, Arno Alpi, Ralf Schnabel, Anton Gartner
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-04-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2660272?pdf=render