Regulation of budding yeast mating-type switching donor preference by the FHA domain of Fkh1.

During Saccharomyces cerevisiae mating-type switching, an HO endonuclease-induced double-strand break (DSB) at MAT is repaired by recombining with one of two donors, HMLα or HMRa, located at opposite ends of chromosome III. MATa cells preferentially recombine with HMLα; this decision depends on the...

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Bibliographic Details
Main Authors: Jin Li, Eric Coïc, Kihoon Lee, Cheng-Sheng Lee, Jung-Ae Kim, Qiuqin Wu, James E Haber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3320585?pdf=render

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