Regulation of budding yeast mating-type switching donor preference by the FHA domain of Fkh1.
During Saccharomyces cerevisiae mating-type switching, an HO endonuclease-induced double-strand break (DSB) at MAT is repaired by recombining with one of two donors, HMLα or HMRa, located at opposite ends of chromosome III. MATa cells preferentially recombine with HMLα; this decision depends on the...
Main Authors: | Jin Li, Eric Coïc, Kihoon Lee, Cheng-Sheng Lee, Jung-Ae Kim, Qiuqin Wu, James E Haber |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3320585?pdf=render |
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