Profiling the expression of pro-metastatic genes in association with the clinicopathological features of primary breast cancer

Profiling the expression of pro-metastatic genes in association with the clinicopathological features of primary breast cancer

Abstract Background Metastasis accounts for ninety percent of breast cancer (BrCa) mortality. Cortactin, Ras homologous gene family member A (RhoA), and Rho-associated kinase (ROCK) raise cellular motility in favor of metastasis. Claudins (CLDN) belong to tight junction integrity and are dysregulate...

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Bibliographic Details
Main Authors: Seyed-Mohammad Mazloomi, Mitra Foroutan-Ghaznavi, Vahid Montazeri, Gholamreza Tavoosidana, Ashraf Fakhrjou, Hojjatollah Nozad-Charoudeh, Saeed Pirouzpanah
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Cancer Cell International
Subjects:
Breast cancer
Lymph node
Metastasis
Cortactin
RhoA
ROCK
Online Access:https://doi.org/10.1186/s12935-020-01708-8

Internet

https://doi.org/10.1186/s12935-020-01708-8

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