Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis

Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis

Surgical site infection (SSI) after craniotomy may lead to devastating outcomes. The traditional management guidelines on SSI after craniotomy have stressed the use of prolonged intravenous (IV) administration of culture-specific antibiotics with concomitant removal of the infected autologous bone a...

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Bibliographic Details
Main Authors: Moon-Jun Sohn, Hae-Won Koo
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Interdisciplinary Neurosurgery
Subjects:
Surgical site infection
Epidural abscess
Antibeads insertion
Online Access:http://www.sciencedirect.com/science/article/pii/S2214751920305971
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spelling doaj-bf90ee4e30344bbc956e15ab39139e672020-12-15T04:10:25ZengElsevierInterdisciplinary Neurosurgery2214-75192021-03-0123101036Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitisMoon-Jun Sohn0Hae-Won Koo1Department of Neurosurgery, Inje University, Ilsan Paik Hospital, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Republic of KoreaCorresponding author at: Department of Neurosurgery, Ilsan Paik Hospital, Inje University, 170 Juhwa-ro, Ilsan-seo-gu, Goyang-si, Gyeonggi-do, 10380, Republic of Korea.; Department of Neurosurgery, Inje University, Ilsan Paik Hospital, Neuroscience, Radiosurgery and Adaptive Hybrid Neurosurgery Research Center, Goyang, Republic of KoreaSurgical site infection (SSI) after craniotomy may lead to devastating outcomes. The traditional management guidelines on SSI after craniotomy have stressed the use of prolonged intravenous (IV) administration of culture-specific antibiotics with concomitant removal of the infected autologous bone and drainage of abscess. However, long-term use of antibiotics can cause problems, such as hepatotoxicity and nephrotoxicity, and can increase social and economic burdens. Here, we first reported three cases of postcraniotomy epidural abscess that were successfully treated by polymethyl methacrylate mixed with antibiotics and concomitant systemic antibiotic use.http://www.sciencedirect.com/science/article/pii/S2214751920305971Surgical site infectionEpidural abscessAntibeads insertion
collection DOAJ
language English
format Article
sources DOAJ
author Moon-Jun Sohn
Hae-Won Koo
spellingShingle Moon-Jun Sohn
Hae-Won Koo
Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
Interdisciplinary Neurosurgery
Surgical site infection
Epidural abscess
Antibeads insertion
author_facet Moon-Jun Sohn
Hae-Won Koo
author_sort Moon-Jun Sohn
title Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
title_short Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
title_full Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
title_fullStr Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
title_full_unstemmed Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
title_sort experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
publisher Elsevier
series Interdisciplinary Neurosurgery
issn 2214-7519
publishDate 2021-03-01
description Surgical site infection (SSI) after craniotomy may lead to devastating outcomes. The traditional management guidelines on SSI after craniotomy have stressed the use of prolonged intravenous (IV) administration of culture-specific antibiotics with concomitant removal of the infected autologous bone and drainage of abscess. However, long-term use of antibiotics can cause problems, such as hepatotoxicity and nephrotoxicity, and can increase social and economic burdens. Here, we first reported three cases of postcraniotomy epidural abscess that were successfully treated by polymethyl methacrylate mixed with antibiotics and concomitant systemic antibiotic use.
topic Surgical site infection
Epidural abscess
Antibeads insertion
url http://www.sciencedirect.com/science/article/pii/S2214751920305971
work_keys_str_mv AT moonjunsohn experienceonantibioticimpregnatedbeadsforintracranialepiduralinfectioncombinedwithosteomyelitis
AT haewonkoo experienceonantibioticimpregnatedbeadsforintracranialepiduralinfectioncombinedwithosteomyelitis
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