Experience on antibiotic-impregnated beads for intracranial epidural infection combined with osteomyelitis
Surgical site infection (SSI) after craniotomy may lead to devastating outcomes. The traditional management guidelines on SSI after craniotomy have stressed the use of prolonged intravenous (IV) administration of culture-specific antibiotics with concomitant removal of the infected autologous bone a...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-03-01
|
| Series: | Interdisciplinary Neurosurgery |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214751920305971 |
| Summary: | Surgical site infection (SSI) after craniotomy may lead to devastating outcomes. The traditional management guidelines on SSI after craniotomy have stressed the use of prolonged intravenous (IV) administration of culture-specific antibiotics with concomitant removal of the infected autologous bone and drainage of abscess. However, long-term use of antibiotics can cause problems, such as hepatotoxicity and nephrotoxicity, and can increase social and economic burdens. Here, we first reported three cases of postcraniotomy epidural abscess that were successfully treated by polymethyl methacrylate mixed with antibiotics and concomitant systemic antibiotic use. |
|---|---|
| ISSN: | 2214-7519 |