The use of in-strip digestion for fast proteomic analysis on tear fluid from dry eye patients.

Tear is an accessible fluid for exploring biomarkers of dry eye disease. This study describes a fast proteomic method by LC-Q-orbitrap-MS analysis with in-strip digestion and investigates the tear proteome of dry eye patients. Schirmer's strips were used for collection of tear fluid from patien...

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Bibliographic Details
Main Authors: Zhu Huang, Chi-Xin Du, Xiao-Dong Pan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6075744?pdf=render