Application of SORTS, a Novel Gene-Edited Cell Selection Method for HIV Study and Therapy

Application of SORTS, a Novel Gene-Edited Cell Selection Method for HIV Study and Therapy

We have recently developed surface oligopeptide knock-in for rapid target selection (SORTS), a novel method to isolate mammalian cells with gene modifications using FACS-sorting. It relies on CRISPR/Cas9-mediated targeted knock-in of a very short promoterless expression construct (250 bp) comprising...

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Bibliographic Details
Main Authors: Dmitriy Mazurov, Alexandra Maslennikova, Dmitriy Komkov, Anastasia Zotova
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:Proceedings
Subjects:
SORTS
CD52
HIV-1
gene editing
CRISPR-Cas9
fusion inhibitor peptides
Online Access:https://www.mdpi.com/2504-3900/50/1/13

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