Application of serine integrases for secondary metabolite pathway assembly in Streptomyces

Application of serine integrases for secondary metabolite pathway assembly in Streptomyces

Serine integrases have been shown to be efficient tools for metabolic pathway assembly. To further improve the flexibility and efficiency of pathway engineering via serine integrases, we explored how multiple orthogonally active serine integrases can be applied for use in vitro for the heterologous...

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Bibliographic Details
Main Authors: Hong Gao, Gabrielle Taylor, Stephanie K. Evans, Paul C.M. Fogg, Margaret C.M. Smith
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-06-01
Series:Synthetic and Systems Biotechnology
Subjects:
Serine integrase
Pathway assembly
Streptomyces
Erythromycin
Online Access:http://www.sciencedirect.com/science/article/pii/S2405805X20300272

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