Centromeric SMC1 promotes centromere clustering and stabilizes meiotic homolog pairing.

During meiosis, each chromosome must selectively pair and synapse with its own unique homolog to enable crossover formation and subsequent segregation. How homolog pairing is maintained in early meiosis to ensure synapsis occurs exclusively between homologs is unknown. We aimed to further understand...

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Bibliographic Details
Main Authors: Talia Hatkevich, Vincent Boudreau, Thomas Rubin, Paul S Maddox, Jean-René Huynh, Jeff Sekelsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1008412