Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development1

Angiotensin II increases vascular proteoglycan content preceding and contributing to atherosclerosis development1

Angiotensin II (angII) is known to promote atherosclerosis; however, the mechanisms involved are not fully understood. To determine whether angII stimulates proteoglycan production and LDL retention, LDL receptor-deficient mice were infused with angII (1,000 ng/kg/min) or saline via osmotic minipump...

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Bibliographic Details
Main Authors: Fei Huang, Joel C. Thompson, Patricia G. Wilson, Hnin H. Aung, John C. Rutledge, Lisa R. Tannock
Format: Article
Language:English
Published: Elsevier 2008-03-01
Series:Journal of Lipid Research
Subjects:
low density lipoprotein retention
biglycan
extracellular matrix
norepinephrine
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520424101

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