Impact of inhibition of Qo site of mitochondrial complex III with myxothiazol on persistent sodium currents via superoxide and protein kinase C in rat hippocampal CA1 cells

Inhibition of Qo site of mitochondrial complex III under hypoxia has received attention, but its downstream pathways remain unclear. We used Qo site inhibitor myxothiazol to mimic the inhibition of the Qo site of complex III and studied the effects of the inhibition of this site on persistent and tr...

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Bibliographic Details
Main Authors: Bin Lai, Li Zhang, Lian-Yan Dong, Yan-Hua Zhu, Feng-Yan Sun, Ping Zheng
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105002019