Synthesis of Bi-heterocyclic Sulfonamides as Tyrosinase Inhibitors: Lineweaver–Burk Plot Evaluation and Computational Ascriptions

Synthesis of Bi-heterocyclic Sulfonamides as Tyrosinase Inhibitors: Lineweaver–Burk Plot Evaluation and Computational Ascriptions

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The designed bi-heterocyclic sulfonamides were synthesized through a two-step protocol and their structures were ascertained by spectral techniques including IR, 1H NMR and 13C NMR along with CHN analysis. The in vitro inhibitory effects of these sulfonamides were evaluated against tyrosinase and ki...

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Bibliographic Details
Main Authors: Muhammad Athar Abbasi, Zia Ur Rehman, Aziz Ur Rehman, Sabhat Zahra Siddiqui, Majid Nazir, Mubashir Hassan, Hussain Raza, Syed Adnan Ali Shah, sung-Yum Seo
Format: Article
Language:English
Published: Slovenian Chemical Society 2020-06-01
Series:Acta Chimica Slovenica
Subjects:
bi-heterocycles
1-phenyl-piperazine
sulfonamides
tyrosinase
chemical kinetics
computational study
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/5283
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