Reverse engineering Boolean networks: from Bernoulli mixture models to rule based systems.

A Boolean network is a graphical model for representing and analyzing the behavior of gene regulatory networks (GRN). In this context, the accurate and efficient reconstruction of a Boolean network is essential for understanding the gene regulation mechanism and the complex relations that exist ther...

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Bibliographic Details
Main Authors: Mehreen Saeed, Maliha Ijaz, Kashif Javed, Haroon Atique Babri
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3524183?pdf=render