Cardiac Fibrosis: Cellular Effectors, Molecular Pathways, and Exosomal Roles

Cardiac fibrosis, a common pathophysiologic process in most heart diseases, refers to an excess of extracellular matrix (ECM) deposition by cardiac fibroblasts (CFs), which can lead to cardiac dysfunction and heart failure subsequently. Not only CFs but also several other cell types including macrop...

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Bibliographic Details
Main Authors: Wenyang Jiang, Yuyan Xiong, Xiaosong Li, Yuejin Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-08-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.715258/full