Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion

Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion

In a pilot study with 6 females and 1 male, the metabolism of various cyanidin glucosides after oral administration of elderberry juice was investigated. The anthocyanin metabolites were detected in urinary excretion. After ingestion of a bolus quantity of 3.57 g total anthocyanins in a 150 mL elder...

Full description

Bibliographic Details
Main Authors: Roland Bitsch, Michael Netzel, Susanne Sonntag, Gabriele Strass, Thomas Frank, Irmgard Bitsch
Format: Article
Language:English
Published: Hindawi Limited 2004-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/S111072430440309X
id doaj-befcf71e37c647cca21317e0717bb269
record_format Article
spelling doaj-befcf71e37c647cca21317e0717bb2692020-11-25T00:50:37ZengHindawi LimitedJournal of Biomedicine and Biotechnology1110-72431110-72512004-01-012004534334510.1155/S111072430440309XUrinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice IngestionRoland Bitsch0Michael Netzel1Susanne Sonntag2Gabriele Strass3Thomas Frank4Irmgard Bitsch5Institute of Nutritional Sciences, Friedrich-Schiller-University Jena, Dornburgerstrasse 29, Jena 07743, GermanyInstitute of Nutritional Sciences, Friedrich-Schiller-University Jena, Dornburgerstrasse 29, Jena 07743, GermanyInstitute of Nutritional Sciences, Friedrich-Schiller-University Jena, Dornburgerstrasse 29, Jena 07743, GermanyInstitute of Nutritional Sciences, Friedrich-Schiller-University Jena, Dornburgerstrasse 29, Jena 07743, GermanyIMFORM GmbH International Clinical Research, Birkenweg 14, Darmstadt 64295, GermanyInstitute of Nutritional Sciences, Justus-Liebig-University Giessen, Wilhelmstrasse 20, Giessen 35392, GermanyIn a pilot study with 6 females and 1 male, the metabolism of various cyanidin glucosides after oral administration of elderberry juice was investigated. The anthocyanin metabolites were detected in urinary excretion. After ingestion of a bolus quantity of 3.57 g total anthocyanins in a 150 mL elderberry juice concentrate, 0.053% of the administered dose was excreted in urine as glucosidically bound cyanidins within the first 5 hours. Only 0.003% of the ingested anthocyanin glucosides was excreted as cyanidin glucuronide, suggesting that this conversion step might be of minor importance in urinary excretion.http://dx.doi.org/10.1155/S111072430440309X
collection DOAJ
language English
format Article
sources DOAJ
author Roland Bitsch
Michael Netzel
Susanne Sonntag
Gabriele Strass
Thomas Frank
Irmgard Bitsch
spellingShingle Roland Bitsch
Michael Netzel
Susanne Sonntag
Gabriele Strass
Thomas Frank
Irmgard Bitsch
Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
Journal of Biomedicine and Biotechnology
author_facet Roland Bitsch
Michael Netzel
Susanne Sonntag
Gabriele Strass
Thomas Frank
Irmgard Bitsch
author_sort Roland Bitsch
title Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
title_short Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
title_full Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
title_fullStr Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
title_full_unstemmed Urinary Excretion of Cyanidin Glucosides and Glucuronides in Healthy Humans After Elderberry Juice Ingestion
title_sort urinary excretion of cyanidin glucosides and glucuronides in healthy humans after elderberry juice ingestion
publisher Hindawi Limited
series Journal of Biomedicine and Biotechnology
issn 1110-7243
1110-7251
publishDate 2004-01-01
description In a pilot study with 6 females and 1 male, the metabolism of various cyanidin glucosides after oral administration of elderberry juice was investigated. The anthocyanin metabolites were detected in urinary excretion. After ingestion of a bolus quantity of 3.57 g total anthocyanins in a 150 mL elderberry juice concentrate, 0.053% of the administered dose was excreted in urine as glucosidically bound cyanidins within the first 5 hours. Only 0.003% of the ingested anthocyanin glucosides was excreted as cyanidin glucuronide, suggesting that this conversion step might be of minor importance in urinary excretion.
url http://dx.doi.org/10.1155/S111072430440309X
work_keys_str_mv AT rolandbitsch urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
AT michaelnetzel urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
AT susannesonntag urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
AT gabrielestrass urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
AT thomasfrank urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
AT irmgardbitsch urinaryexcretionofcyanidinglucosidesandglucuronidesinhealthyhumansafterelderberryjuiceingestion
_version_ 1725247506683527168

Similar Items