DNA methylation profiling in mummified human remains from the eighteenth-century

Abstract Reconstruction of ancient epigenomes by DNA methylation (DNAm) can shed light into the composition of cell types, disease states, and age at death. However, such analysis is hampered by impaired DNA quality and little is known how decomposition affects DNAm. In this study, we determined if...

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Bibliographic Details
Main Authors: Marco Schmidt, Frank Maixner, Gerhard Hotz, Ildikó Pap, Ildikó Szikossy, György Pálfi, Albert Zink, Wolfgang Wagner
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95021-7