Palmitic Acid and Ergosta-7,22-dien-3-ol Contribute to the Apoptotic Effect and Cell Cycle Arrest of an Extract from Marthasterias glacialis L. in Neuroblastoma Cells

Palmitic Acid and Ergosta-7,22-dien-3-ol Contribute to the Apoptotic Effect and Cell Cycle Arrest of an Extract from Marthasterias glacialis L. in Neuroblastoma Cells

We describe the effect of a chemically characterized lipophilic extract obtained from Marthasterias glacialis L. against human breast cancer (MCF-7) and human neuroblastoma (SH-SY5Y) cell lines. Evaluation of DNA synthesis revealed that both cell lines were markedly affected in a concentration-depen...

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Bibliographic Details
Main Authors: David M. Pereira, Georgina Correia-da-Silva, Patrícia Valentão, Natércia Teixeira, Paula B. Andrade
Format: Article
Language:English
Published: MDPI AG 2013-12-01
Series:Marine Drugs
Subjects:
Marthasterias glacialis L.
palmitic acid
ER-stress
CHOP
apoptosis
Online Access:http://www.mdpi.com/1660-3397/12/1/54

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http://www.mdpi.com/1660-3397/12/1/54

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