DA-9801 and its saponins, dioscin and protodioscin, protect primary cortical neurons from hyperglycemia-induced neurotoxicity

Neurodegenerative diseases, including Alzheimer’s disease, are prevalent in diabetic patients. DA-9801 is a standardized extract of Dioscorea japonica Thunb. and Dioscorea nipponica Makino, which has been shown to reduce blood glucose levels and exert protective effects against diabetic peripheral n...

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Bibliographic Details
Main Authors: Ha-Rim Lee, Sun-Young Kong, Sang Hyun Sung, Hyun-Jung Kim
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464619300222