Double-stranded RNA production and the kinetics of recombinant Escherichia coli HT115 in fed-batch culture

Double-stranded RNA can induce interference processes. The specificity of this system raises the possibility of using dsRNA for therapeutic applications targeting viral diseases. Escherichia coli HT115 (DE3) has been widely used to produce dsRNA; however, the kinetics of dsRNA production and the rel...

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Bibliographic Details
Main Authors: Ljubomir Papić, José Rivas, Soledad Toledo, Jaime Romero
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Biotechnology Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2215017X17300346