Isolated Right Ventricular Non-compaction in a Neonate Born to a Mother with Gestational Diabetes: A Case Report

• Main Authors: Yazdan Ghandi, Sarvenaz Mehrabi, Saeed Alinejad
• Format: Article
• Language: English
• Published: Mashhad University of Medical Sciences 2020-10-01
• Series: Iranian Journal of Neonatology
• Subjects: cardiomyopathy; gestational diabetes; newborn; right ventricular non-compaction; tension pneumothorax
• Online Access: http://ijn.mums.ac.ir/article_16322_fafca05be11e7ce866bd95d7515511a9.pdf

Background: Ventricular non-compaction, which is a rare congenital cardiomyopathy, results from an arrest in normal endomyocardial embryogenesis. It is characterized by a pattern of prominent trabecular meshwork and deep inter-trabecular recesses. The clinical manifestations include systolic and diastolic dysfunctions, heart failure, ventricular arrhythmias, and cardioembolic events.Case report: Here we present the case of a neonate (38 weeks, weighing 2580 gr) born to a mother with gestational diabetes (GDM) with isolated right ventricular non-compaction (IRVNC) and systolic and diastolic right heart dysfunction due to meconium aspiration syndrome and tension pneumothorax. A 4-month follow-up demonstrated a complete improvement in the newborn.Conclusion: It is of paramount importance to consider RVNC cardiomyopathy a differential diagnosis of cyanosis and respiratory distress due to meconium aspiration syndrome in neonate s born to mothers with GDM. Apart from RV cardiac dysfunction, RVNC could cause such complications as pulmonary hypertension and tension pneumothorax. It can be also spontaneously improved in GMD.