Vaginal delivery in women with COVID-19: report of two cases

Abstract Background During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. Case presentation Case 1: A 35-year-old pregnant woman with...

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Main Authors: Dongmei Cao, Miaomiao Chen, Min Peng, Heng Yin, Guoqiang Sun
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Pregnancy and Childbirth
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12884-020-03281-4
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spelling doaj-bebbeb7b0b17480b9a61bca3b7cd5bad2020-11-25T03:40:00ZengBMCBMC Pregnancy and Childbirth1471-23932020-10-012011610.1186/s12884-020-03281-4Vaginal delivery in women with COVID-19: report of two casesDongmei Cao0Miaomiao Chen1Min Peng2Heng Yin3Guoqiang Sun4Department of Obstetrics, Maternal and Child Health Hospital of Hubei ProvinceDepartment of Obstetrics, Maternal and Child Health Hospital of Hubei ProvinceDepartment of Obstetrics, Maternal and Child Health Hospital of Hubei ProvinceDepartment of Obstetrics, Maternal and Child Health Hospital of Hubei ProvinceDepartment of Obstetrics, Maternal and Child Health Hospital of Hubei ProvinceAbstract Background During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. Case presentation Case 1: A 35-year-old pregnant woman with a gestational age of 37 weeks and 6 days was admitted to our hospital at the point of giving birth. Except for the abnormalities in her chest CT image, she was asymptomatic. She had an uncomplicated spontaneous vaginal delivery, and her infant was discharged home for isolation. Because of the positive result of the maternal swabs for SARS-CoV-2 obtained on the 2nd day after sampling, we transferred the mother to the designated hospital and followed up with her by telephone interviews. Luckily, it was confirmed on February 23 that the newborn did not develop any COVID-19 symptoms after observation for 14 days after birth. Case 2: Another pregnant woman, with a gestational age of 38 weeks and 2 days, was also admitted to our hospital because of spontaneous labor with cervical dilation of 5 cm. Since she had the typical manifestations of COVID-19, including cough, lymphopenia, and abnormal chest CT images, she was highly suspected of having COVID-19. Based on the experience from case 1, we helped the mother deliver a healthy baby by vaginal delivery. On the 2nd day after delivery, the maternal nasopharyngeal swab result was positive, while the infant’s result was negative. Conclusion There is still insufficient evidence supporting maternal-fetal vertical transmission for COVID-19-infected mothers in late pregnancy, and vaginal delivery may not increase the possibility of neonatal infection.http://link.springer.com/article/10.1186/s12884-020-03281-4COVID-19Vaginal deliveryIntrauterine vertical transmissionCase report
collection DOAJ
language English
format Article
sources DOAJ
author Dongmei Cao
Miaomiao Chen
Min Peng
Heng Yin
Guoqiang Sun
spellingShingle Dongmei Cao
Miaomiao Chen
Min Peng
Heng Yin
Guoqiang Sun
Vaginal delivery in women with COVID-19: report of two cases
BMC Pregnancy and Childbirth
COVID-19
Vaginal delivery
Intrauterine vertical transmission
Case report
author_facet Dongmei Cao
Miaomiao Chen
Min Peng
Heng Yin
Guoqiang Sun
author_sort Dongmei Cao
title Vaginal delivery in women with COVID-19: report of two cases
title_short Vaginal delivery in women with COVID-19: report of two cases
title_full Vaginal delivery in women with COVID-19: report of two cases
title_fullStr Vaginal delivery in women with COVID-19: report of two cases
title_full_unstemmed Vaginal delivery in women with COVID-19: report of two cases
title_sort vaginal delivery in women with covid-19: report of two cases
publisher BMC
series BMC Pregnancy and Childbirth
issn 1471-2393
publishDate 2020-10-01
description Abstract Background During the ongoing global outbreak of COVID-19, pregnant women who are susceptible to COVID-19 should be highly concerned. The issue of vertical transmission and the possibility of neonatal infection is a major concern. Case presentation Case 1: A 35-year-old pregnant woman with a gestational age of 37 weeks and 6 days was admitted to our hospital at the point of giving birth. Except for the abnormalities in her chest CT image, she was asymptomatic. She had an uncomplicated spontaneous vaginal delivery, and her infant was discharged home for isolation. Because of the positive result of the maternal swabs for SARS-CoV-2 obtained on the 2nd day after sampling, we transferred the mother to the designated hospital and followed up with her by telephone interviews. Luckily, it was confirmed on February 23 that the newborn did not develop any COVID-19 symptoms after observation for 14 days after birth. Case 2: Another pregnant woman, with a gestational age of 38 weeks and 2 days, was also admitted to our hospital because of spontaneous labor with cervical dilation of 5 cm. Since she had the typical manifestations of COVID-19, including cough, lymphopenia, and abnormal chest CT images, she was highly suspected of having COVID-19. Based on the experience from case 1, we helped the mother deliver a healthy baby by vaginal delivery. On the 2nd day after delivery, the maternal nasopharyngeal swab result was positive, while the infant’s result was negative. Conclusion There is still insufficient evidence supporting maternal-fetal vertical transmission for COVID-19-infected mothers in late pregnancy, and vaginal delivery may not increase the possibility of neonatal infection.
topic COVID-19
Vaginal delivery
Intrauterine vertical transmission
Case report
url http://link.springer.com/article/10.1186/s12884-020-03281-4
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AT hengyin vaginaldeliveryinwomenwithcovid19reportoftwocases
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