Health Effects of Grape Seed and Skin Extracts and Their Influence on Biochemical Markers

• Main Authors: Lenka Sochorova, Bozena Prusova, Martina Cebova, Tunde Jurikova, Jiri Mlcek, Anna Adamkova, Sarka Nedomova, Mojmir Baron, Jiri Sochor
• Format: Article
• Language: English
• Published: MDPI AG 2020-11-01
• Series: Molecules
• Subjects: antioxidants; cancer; cardiovascular disease; diabetes mellitus; gastrointestinal tract; grape seeds
• Online Access: https://www.mdpi.com/1420-3049/25/22/5311

This review is focused on the study of the effects of grape seed and skin extract (GSSE) on human health. GSSE contains high concentrations of important polyphenolic substances with high biological activity. This review is a summary of studies that investigate the effects of GSSE on diabetes mellitus, cardiovascular disease and cancer, its neuroprotective effect, and its effects on the gastrointestinal tract and other health complications related to these diseases. The results of the studies confirm that the anti-inflammatory, antiapoptotic, and pro-proliferative effects of “<i>Vitis vinifera</i> L.” seed extract reduce the level of oxidative stress and improve the overall lipid metabolism.