Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models

Immersion in Raloxifene does not significantly improve bone toughness or screw pull-out strength in multiple in vitro models

Abstract Background Failure of surgical fixation in orthopaedic fractures occurs at a significantly higher rate in osteoporotic patients due to weakened osteoporotic bone. A therapy to acutely improve the mechanical properties of bone during fracture repair would have profound clinical impact. A pre...

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Bibliographic Details
Main Authors: Michael R. Eby, Danielle M. Cristino, Matthew Counihan, Kendall M. Masada, Jaimo Ahn, Michael W. Hast
Format: Article
Language:English
Published: BMC 2021-05-01
Series:BMC Musculoskeletal Disorders
Subjects:
Raloxifene
Fracture repair
Proximal humerus
Cadaveric
Biomechanics
Online Access:https://doi.org/10.1186/s12891-021-04342-1

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