Prediction of microbial growth rate versus biomass yield by a metabolic network with kinetic parameters.

Identifying the factors that determine microbial growth rate under various environmental and genetic conditions is a major challenge of systems biology. While current genome-scale metabolic modeling approaches enable us to successfully predict a variety of metabolic phenotypes, including maximal bio...

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Bibliographic Details
Main Authors: Roi Adadi, Benjamin Volkmer, Ron Milo, Matthias Heinemann, Tomer Shlomi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3390398?pdf=render