Supplemental N-3 Polyunsaturated Fatty Acids Limit A1-Specific Astrocyte Polarization via Attenuating Mitochondrial Dysfunction in Ischemic Stroke in Mice

Ischemic stroke is one of the leading causes of death and disability for adults, which lacks effective treatments. Dietary intake of n-3 polyunsaturated fatty acids (n-3 PUFAs) exerts beneficial effects on ischemic stroke by attenuating neuron death and inflammation induced by microglial activation....

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Bibliographic Details
Main Authors: Jun Cao, Lijun Dong, Jialiang Luo, Fanning Zeng, Zexuan Hong, Yunzhi Liu, YiBo Zhao, Zhengyuan Xia, Daming Zuo, Li Xu, Tao Tao
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2021/5524705