FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling

FKBP4 integrates FKBP4/Hsp90/IKK with FKBP4/Hsp70/RelA complex to promote lung adenocarcinoma progression via IKK/NF-κB signaling

Abstract FKBP4 belongs to the family of immunophilins, which serve as a regulator for steroid receptor activity. Thus, FKBP4 has been recognized to play a critical role in several hormone-dependent cancers, including breast and prostate cancer. However, there is still no research to address the role...

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Bibliographic Details
Main Authors: Shuai Zong, Yulian Jiao, Xin Liu, Wenli Mu, Xiaotian Yuan, Yunyun Qu, Yu Xia, Shuang Liu, Huanxin Sun, Laicheng Wang, Bin Cui, Xiaowen Liu, Ping Li, Yueran Zhao
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03857-8

Internet

https://doi.org/10.1038/s41419-021-03857-8

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