Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators

Single-Cell Transcriptomics Reveals Spatial and Temporal Turnover of Keratinocyte Differentiation Regulators

Keratinocyte differentiation requires intricately coordinated spatiotemporal expression changes that specify epidermis structure and function. This article utilizes single-cell RNA-seq data from 22,338 human foreskin keratinocytes to reconstruct the transcriptional regulation of skin development and...

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Bibliographic Details
Main Authors: Alex Finnegan, Raymond J. Cho, Alan Luu, Paymann Harirchian, Jerry Lee, Jeffrey B. Cheng, Jun S. Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Genetics
Subjects:
Single-cell analysis
transcription regulation
keratinocyte
antioxidant
differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00775/full

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