Diagnostic accuracy of PCR in gambiense sleeping sickness diagnosis, staging and post-treatment follow-up: a 2-year longitudinal study.

BACKGROUND:The polymerase chain reaction (PCR) has been proposed for diagnosis, staging and post-treatment follow-up of sleeping sickness but no large-scale clinical evaluations of its diagnostic accuracy have taken place yet. METHODOLOGY/PRINCIPAL FINDINGS:An 18S ribosomal RNA gene targeting PCR wa...

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Bibliographic Details
Main Authors: Stijn Deborggraeve, Veerle Lejon, Rosine Ali Ekangu, Dieudonné Mumba Ngoyi, Patient Pati Pyana, Médard Ilunga, Jean Pierre Mulunda, Philippe Büscher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3042993?pdf=render