Complement and Chlamydia psittaci: Early Complement-Dependent Events Are Important for DC Migration and Protection During Mouse Lung Infection

The zoonotic intracellular bacterium Chlamydia psittaci causes life-threatening pneumonia in humans. During mouse lung infection, complement factor C3 and the anaphylatoxin C3a augment protection against C. psittaci by a so far unknown mechanism. To clarify how complement contributes to the early, i...

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Bibliographic Details
Main Authors: Martin Kohn, Christian Lanfermann, Robert Laudeley, Silke Glage, Claudia Rheinheimer, Andreas Klos
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
C3a
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.580594/full